Synact nådde inte målen i studie: ”Vi är besvikna”

Lundbaserade Synact Pharma nådde inte sitt primära mål i fas IIb-studien Expand, där läkemedelskandidaten resomelagon utvärderades för patienter med svår aktiv nydiagnostiserad reumatoid artrit. Beskedet fick bolagets aktie att falla kraftigt.

By Anders Göransson

September 4, 2023 11:01 AM

I studien jämfördes resomelagon med placebo enligt American College of Rheumatologys måttskala ACR20 (en 20-procentig förbättring) efter 12 veckor.

Resultaten visade, förvånande nog, att en större andel av deltagarna i placebogruppen fick ett ACR20-svar än i gruppen som fick den aktiva behandlingen, 55,7 procent jämfört med 54,7 procent.

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